Determination of copper in plasma and serum by use of a microsampling cup in atomic absorption spectrometry.
نویسندگان
چکیده
A microsampling cup procedure is described for rapid, precise determination of copper in plasma. Conventional Delves-cup atomic absorption spectrometry does not yield usable copper signals with blood plasma samples. Analytical sensitivity was improved 11-fold by use of cups fitted with an axial hole, a triangular cup-holding loop, and a smaller-bore absorption tube. The modified procedure yields relative standard deviations of 4-6% at the level of 95 tg of copper per deciliter. Analysis of 100 samples of blood plasma by both the microsampling cup procedure and a solvent-extraction atomic absorption procedure showed no significant difference between the two sets of data (P <.02).
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 20 9 شماره
صفحات -
تاریخ انتشار 1974